Accumulating evidence shows that CYP1A1 polymorphisms are associated with an increased susceptibility to cancer (Bartsch et al., 2000; Bozina et al., 2009; Androutsopoulos et al., 2009); due to alterations to mRNA expression and enzymatic activity (Cosma et al., 1993; Crofts et al., 1994, and Schwarz et al., 2001). This evidence concerns the gene CYP1A1 and cancer.