In the current study, PDL-1 expression in tumor cells was positively correlated with right sided tumors (44.4%) compatible with Lee et al., (2016) who stated that PDL-1 expression was higher in right colonic tumors (63%) than left sided one (37%), Inaguma et al., (2017) (46% in right sided tumors, 15% in transverse, 31% in left side tumors and 9% in rectum) and Valentini et al., (2018) (81.25% in right side tumors and 18.75% in left side tumors). The gene discussed is CD274; the disease is colonic neoplasm.