CXCL12 and cancer: One of CSC markers which involved in hematopoietic stem cell (HSC) mobilization (Gelmini et al., 2008) and homing and other cancers metastasis (Zhang et al., 2012; Hermann et al., 2007) is the chemokine SDF1/CXCL12 and its receptor CXCR4 (Adhikari et al., 2010).