CCR7 and neoplasm: Thus, CCR7 plays an important role in lymphocyte homing to LNs and spleen.24 It has been demonstrated that in CCR7‐deficient mice T lymphocytes are absent in the lymphoid white pulp of LNs and spleen, and are present only in the red pulp of the spleen.25, 26 Tumour‐associated MCs can release a variety of cytokines, chemokines and growth factors, promoting tumour development by enhancing angiogenesis and remodelling tumour extracellular matrix.27, 28, 29