BRD2 and central congenital hypothyroidism: In the 53 patients in whom complete data were available, endocrine outcomes at last follow-up assessment were as follows: TSH deficiency (36/53; 67.9%), followed by ACTH deficiency (27/53; 50.9%), FSH and LH deficiency (26/53; 49.1%) and GH deficiency (16/53; 30.1%).