NEB and nemaline myopathy: Nebulin was suggested to be involved in thin filament length regulation, because reduced nebulin protein levels result in abnormal thin filament lengths in NEB-related nemaline myopathy patients as well as in nebulin deficient mouse models, zebrafish and chick skeletal myocytes (Bang et al. 2006; de Winter et al. 2016; Ottenheijm et al. 2009, 2010, 2013; Pappas et al. 2008; Telfer et al. 2012; Witt et al. 2006).