CXCL10 in blood further rose when in addition to mere BKPyV DNAuria low‐level DNAemia emerged (median increase: 52.60 pg/ml, 95% CI: 41.55–78.82, P = 0.001) and further increased when low‐level DNAemia progressed to DNA loads ≥1000 copies/ml, but no evidence for PVAN was yet detected (decoy cells <20%, no eGFR decrease; median increase: 87.26 pg/ml, 95% CI: 55.42–153.51, P = 0.0002). This evidence concerns the gene CXCL10 and BK-virus nephropathy.