AFDN divergent transcript (AFDN‐DT), also known as MLLT4 antisense RNA 1 (MLLT4‐AS1), is an lncRNA located upstream of the Afadin (AFDN) gene.20 AFDN, otherwise known as MLLT4 and AF6, has been identified as a fusion partner in Lysine Methyltransferase 2A gene (KMT2A).21 In our previous study, we showed that high levels of AFDN‐DT, but not AFDN, correlated with a favourable outcome in patients with GC20 and suggested that AFDN‐DT might be tumour suppressor, even though the mechanism of AFDN‐DT in GC remains completely unknown. Here, AFDN is linked to neoplasm.