FERMT2 and Glucose intolerance: The littermates generated from breeding, including the wild-type (WT) mice that contain no Cre or floxed Kindlin-2 genes, Kindlin-2 flox heterozygotes that harbor RIP-Cre (i.e., RIP-Cre; Kindlin-2fl/+), Cre-negative floxed Kindlin-2 mice (i.e., Kindlin-2fl/fl) or Cre transgenic mice (i.e., RIP-Cre), were viable and fertile and did not display marked glucose intolerance (Fig. 1b).