Additionally, we also found that α-MGT inhibited the phosphorylation of Tyr705 in STAT3 (Fig. 7g, k) and induced the expression of SHP1 (Fig. 7h, l) in xenograft tumors in mice bearing HepG2 cells and SK-Hep-1 HCC cells. The gene discussed is STAT3; the disease is hepatocellular carcinoma.