CCK and hydrops fetalis: In contrast, no enhancement in the neuronal response to the VS was observed in the AC of CCK−/− mice with the same manipulation (Fig. 4P, two-way ANOVA F(1,15) = 5.767, p = 0.0297 significant interaction; pairwise comparison, after pairing, CCK-ires-Cre (n = 9) vs CCK−/− (n = 8), 5.6 ± 0.41 vs 0.43 ± 0.44, p < 0.001; pairwise comparison, CCK-ires-Cre before vs after, 3.9 ± 0.34 vs 5.6 ± 0.41, p < 0.001; pairwise comparison, CCK−/−, before vs after, 0.51 ± 0.36 vs 0.43 ± 0.44, p = 0.885) suggesting that CCK is a key molecule responsible for such HF-induced LFP enhancement.