MTOR and cervical squamous intraepithelial neoplasia: Intriguingly, we found that the mTor inhibitor AZD8055 (compound #1561) at 0.1 μM acted synergistically with CIN in reducing cell numbers (31% greater than additive effect; P = 2.7E-4, Bliss independence test) during the first 4 d of the screen, but became fully toxic to both control and Mad2cKD cells from day 5 onward (Fig 3A and B and Supplemental Data 2 for all growth curves).