It is likely that the growth defects we observed after combined Src and SAC inhibition are caused by a combination of cell cycle arrest and cell death (for a recent review on this topic, see Chunduri & Storchová (2019)) and that whether cells arrest or undergo apoptosis depends on the karyotypes that the aneuploid cells acquired after the CIN insult. Here, ADCY10 is linked to cervical squamous intraepithelial neoplasia.