The abundance ratio of cancer/liver cirrhosis of each protein was as follows: GPC3 (1.49, p = 0.003), SCCA (1.4, p = 0.024), haptoglobin (2.25, p = 0.038), C3 (1.38, p = 0.005), seprase (1.33, p < 0.001), Hb-γ (3.72, p = 0.021), Hb-α (6.25, p = 0.006), and teneurin3 (2.73, p = 0.004), respectively. This evidence concerns the gene C3 and cancer.