Our inheritance test model revealed that the STAT6 (rs3024974) gene polymorphism did not increase the risk of malaria with the dominant (G/A-A/A versus G/G; OR = 0.98; 95% CI = 0.67–1.44) or recessive allele (G/G-G/A versus A/A; OR = 0.62; 95% CI = 0.32–1.20). This evidence concerns the gene STAT6 and malaria.