ACHE and Alzheimer disease: Samples were then chemically profiled by high-performance liquid chromatography coupled to mass spectrometry (HPLC-MS), and evaluated for in vitro enzymatic inhibitory properties towards key enzymes in human diseases, namely Alzheimer’s disease (AD), (acetyl- and butyrylcholinesterase, AChE, BuChE), Type-2 diabetes (α-glucosidase and α-amylase), and hyperpigmentation (tyrosinase).