AKT1 and acute myeloid leukemia: In a group of acute myeloid leukemia (AML) cell lines harboring FLT3 mutation (FLT3 is a commonly mutated gene in AML), EGCG 60 μM (and (−)-epigallocatechin (EGC), (−)-epicatechin-3-gallate (ECG), and (+)-Catechin (C)) showed reduced levels of FLT3 and the suppression of phosphorylated MAPK, AKT, and STAT5 [143].