SERPINE1 and asthma: It has been seen that in individuals suffering from asthma there is overexpression of numerous genes and proteins, such as Signal Transducer and Activator of Transcription 6 (STAT6) [4], Plasminogen Activator Inhibitor-1 (PAI-1) [5], and Spleen Tyrosine Kinase (Syk) [6].