Within our on-going studies on GRPr-targeted nanotools, we have evaluated some radiolabeled AuNPs stabilized with an acyclic DTPA derivative (DTTPA = (2-[bis[2-[carboxymethyl-[2-oxo-2-(2-sulfanylethylamino)ethyl]amino]ethyl]amino]acetic acid) or with a macrocyclic DOTA derivative (TDOTA = trimethyl 2,2′,2′′-(10-2(3-(tritylthio)propamido)ethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-trityl)triacetate), and functionalized with BBN analogue peptides for specific tumor targeting. Here, GRPR is linked to neoplasm.