These results regarding the pro-apoptotic role played by resveratrol are in agreement with previous data obtained from acute myeloid leukemia (AML) cells reporting the subsequent induction of DNA repair enzyme PARP (poly adenosine diphosphate (ADP)-ribose polymerase) cleavage due to cysteine protease Caspase-3 activation occurring upon treatment with the compound [95]. The gene discussed is LIG4; the disease is acute myeloid leukemia.