However, in study of Lin et al, they associated the ‐173*C MIF polymorphisms with the risk of BC, demonstrating that ‐173*C allele increases the risk of BC especially in older women of Chinese population.25 Also, other study suggests that MIF ‐173G > C polymorphism was associated with the participation of developing cancer, preponderantly in prostate cancer.23 Here, MIF is linked to Familial prostate cancer.