Regulatory T cells (Tregs) have also been implicated as an important player in limiting T cell responses during infection with T. gondii. During the acute stage of infection, increasing Treg numbers using treatment with IL-2 complexes resulted in decreased inflammation and immunopathology in the small intestine and liver, but was associated with increased parasite burden in the brain in the later stage of infection [8]. This evidence concerns the gene IL2 and infection.