Whereas PSV EE was significantly associated with trans-infection (P = .0001, r = .9525), irrespective of whether pseudovirus was first bound to Raji cells or MDDCs (S1A and S1B Fig), a correlation was only found between DC-SIGN binding and trans-infection when Raji-DC-SIGN cells were used as the vehicle (S1C Fig). Here, CD209 is linked to infection.