RHOA and neoplasm: However, previous reports indicated that RhoA was correlated with OS [19–22, 24], DFS [19], T category (the extent of the primary tumor) [20, 24], TNM stage (international cancer classification system defined by UICC (Union for International Cancer Control)) [20, 22–24, 26] and tumor differentiation [21, 22, 27, 28].