SREBF1 and atherosclerosis: Indeed, several research groups identified agents that can reduce atherosclerosis without activating SREBP-1c or increasing hepatic lipogenesis, such as taurine, taurine, ethyl 2,4,6-trihydroxybenzoate, WAY-252623, and N,N-dimethyl-3β-hydroxy-cholenamide [32, 35, 36].