Among the 10 hub DMGs revealed, six (STAT3, PTPN6, SYK, STAT5B, XPO1, and ABL1) had known CLL relevance (blue tint), whereas the remaining four (UBC, GRB2, CREBBP, and GAB2) did not. The gene discussed is PTPN6; the disease is B-cell chronic lymphocytic leukemia.