Of note, in a study directly comparing gene expression in healthy and cancerous colorectal tissues, PLIN2 expression (but neither PLIN1, nor PLIN3) strongly correlated with TGF-β2 expression (Fig. 4q); a similar co-expression pattern between TGF-β2 and PLIN2 was also found in human clear cell renal cell carcinoma samples (Supplementary Fig. 4p). Here, PLIN2 is linked to clear cell renal carcinoma.