FOXA1 and prostate neoplasm: Next, considering that noncoding SNVs can target a set of CREs that converge on the same target gene in cancer32, we overlapped the somatic SNVs called from the whole-genome sequencing across 200 primary prostate tumors to the 33 H3K27ac-marked DHS predicted to regulate FOXA1 (Supplementary Data)6,40.