THBS4 and peritonitis: Surprisingly, TSP-4 deletion in the Thbs4−/− mice did not reduce the number of macrophages recovered in a saline lavage (free macrophages) compared with WT mice, but we collected fewer macrophages from the cavity of P387-TSP-4-KI mice than from WT mice after LPS-induced peritonitis (Fig. 6a).