The overexpressed proteins were in glycolysis (Pgk1), the pentose phosphate pathway (Tkl1) and proline biosynthesis (Pro2), whereas the underexpressed proteins were in the EGF receptor signaling pathway (Bmh2), the GF signalling pathway (Bmh2), glutamine glutamate conversion (Gdh1), lysine biosynthesis (Hom6), Parkinson’s disease (Bmh2), pyruvate metabolism (Cdc19) and threonine biosynthesis (Hom6). Here, MCM2 is linked to Parkinson disease.