Our analysis revealed that BMP5 was down-regulated in breast, coloretal, lung, bladder and ovarian cancers, but was over-expressed only in brain and CNS cancers as compared to that in normal tissue (Figure 2A–F and Supplementary Table S1) [37,38,39,40,41,42,43,44,45,46,47,48,49,50,51,52]. Here, BMP5 is linked to central nervous system cancer.