INS and type 2 diabetes mellitus: It is worth noting that decreased fat intake occurred independently of T2D remission, but even patients who did not achieve this metabolic benefit experienced an improvement of markers of glucoses homeostasis (decreased fasting glucose, glycated hemoglobin, fasting insulin, and insulin resistance) after RYGB and have a similar postoperative reduction of HOMA-IR values than patients with T2D remission (p > 0.050; Supplementary Figure S1).