IL1A and psoriasis: In line with a keratinocyte-centralized view of the pathogenesis of psoriasis [57], keratinocyte-specific DEGs (e.g., SERPINB4, S100s, TCN1, KRT16) [58] and IL1 family cytokines (e.g., IL1F5/6/8/9) [59] are highly prevalent in lesional skin.