Studying the association between IGF1 levels and longevity (survival) in specific patient groups appears to be interesting as well, for example, following the growing interest in ghrelin receptor agonists targeting the GH-IGF1 axis to potentially reverse the anorexia–cachexia syndrome in a variety of conditions, including renal insufficiency [12,13,14,15]. This evidence concerns the gene IGF1 and Renal insufficiency.