The final stepwise backward model featured an adjusted R2 of 0.14 and revealed significant positive associations between plasma IGF1 and both 24 h urinary creatinine excretion and calcineurin inhibitor use, but also significant inverse associations with the prevalence of diabetes mellitus as primary renal disease, GGT, HDL cholesterol, and hs-CRP. The gene discussed is IGF1; the disease is kidney disorder.