NOP14 nucleolar protein (NOP14) is frequently identified as a regulator involved in pre‐18s rRNA processing and small ribosomal subunit assembly.34 A previous study demonstrated that NOP14 enhances the stability of mutp53, enabling mutp53 to participate in the progression of pancreatic cancer.35 NOP14 could suppress cancer metastasis by regulating the Wnt/β‐catenin signalling pathway in cancers.36, 37 In our research, we found that NOP14 is involved in cell proliferation and migration and induces apoptosis in BCa cells. The gene discussed is NOP14; the disease is cancer.