The ONCOMINE database was used to analyse DNMT3B expression in 81 patients with Infiltrating Bladder Urothelial Carcinoma, 28 patients with superficial bladder cancer and 48 patients without bladder cancer.27 Results demonstrated a significant upregulation in DNMT3B in bladder cancer compared with normal persons. The gene discussed is DNMT3B; the disease is bladder transitional cell carcinoma.