Zymosan induced the release of IL‐6 and IL‐8, which is stimulated through activating the MAPK and NF‐κB pathways.49 Most of the publicized papers reported IL‐8 as an efficient predictor for bacteremia, while quite few papers are concerned with the changes of IL‐8 during fungal infection. This evidence concerns the gene NFKB1 and bacterial infectious disease with sepsis.