There was a significant association between the presence of STAS and lymph node metastasis (P = .005) as well as pathologic N stage (P = .012), pathologic stage (P = .013), the presence of VPI (P = .012), Twist expression (P < .001) and Slug expression (P = .011). Here, SNAI2 is linked to metastatic malignant neoplasm in the lymph nodes.