ICI‐induced bile duct obstruction and cholangitis have been reported, and they should be considered as causes of cholangitis.12 Patients presented with fever, abdominal discomfort, fatigue, predominant elevation of alkaline phosphatase (ALP) and gamma‐glutamyl‐transpeptidase (GGT), and moderate elevation of transaminases (ALT/AST) and total bilirubin. This evidence concerns the gene GGTLC1 and cholangitis.