Of the 13 datasets analyzed, all of which compared HSP90B1 expression in lung cancer and normal lung tissue, 10 studies consistently showed that HSP90B1 was upregulated in lung cancer tissue, one study indicated that HSP90B1 was downregulated in lung carcinoid tumors, and two studies showed no differential gene expression (Table 1). This evidence concerns the gene HSP90B1 and lung cancer.