The results displayed in Figure 4B suggested that HCC cells cotransfected by SUMO1P3 wt and miR‐320a mimic exhibited obviously low luciferase activity than those cotransfected by SUMO1P3 wt and mimic NC (P < .01), while the cotransfection with miR‐320a mimic and SUMO1P3 mt did not significantly affect luciferase activity of the cells, compared to the control (P > .05). The gene discussed is SUMO1P3; the disease is hepatocellular carcinoma.