On the other hand, CNLs in FCA B1 1–23 Mb (human homologue region located in HSA 8p) were significant in multivariate analysis and harboured multiple tumour suppressors (e.g. CSMD1, MSR1, MTUS1, and TUSC3) previously correlated with poor prognosis in HBCs15,19,23,27,70. Here, TUSC3 is linked to neoplasm.