ATP7A and neuroblastoma: Previous studies showed that overexpressing the ATP7A p.T994I mutant protein in the spinal cord/neuroblastoma hybrid cell line (NSC-34) led to mutant ATP7A re-localizing from the TGN compartments to the cell body's plasma membrane under basal Cu conditions and to the axonal plasma membrane after NSC-34 differentiation (Yi et al., 2012).