Recently, some new etiologies of chILD such as the coatomer protein, subunit alpha (COPA) syndrome and stimulator of interferon genes (STING)–associated vasculopathy with onset in infancy (SAVI) were reported with the development of genetic technologies, which expanded the etiologic spectrum of chILD. This evidence concerns the gene STING1 and STING-associated vasculopathy with onset in infancy.