Seven variants (GCK c.494T>C, GCK c.563C>G, HNF1A c.1623G>A, HNF1A c.1729C>G, HNF4A c.68delG, HNF4A c.422G>C, HNF4A c.602A>C) have not previously been reported in patients with MODY and were found to be absent or very rare (≤0.0001) in the gnomAD population database [8] (Table 1). Here, HNF4A is linked to MODY.