Table 1 presents the clinicopathological backgrounds of 154 patients with NMIBC, and of 58 patients with MIBC. Clinicopathological variables were compared with DAB2 expression in cancerous areas (high and low expression levels). The pathological characteristics, including clinical T stage, tumor grade, the presence of carcinoma in situ, histological variants and tumor infiltrative patterns, were significantly different between patients with low and high DAB2 expression. Similar results were observed in stromal areas (Table S1). The gene discussed is DAB2; the disease is in situ carcinoma.