A correlation has also been reported between changes in the content of IL-34 into these biological fluids and disease parameters in various pathological conditions, such as rheumatoid arthritis (RA), systemic lupus erythematosus, heart failure, viral infections, sepsis, periodontal disease, nonalcoholic fatty liver disease, obesity, and type 2 diabetes mellitus [32]. The gene discussed is IL34; the disease is rheumatoid arthritis.