Deng M and his group reported similar results in a study based on multiple myeloma.31 We also gathered evidence implicating that the down‐regulated LINC00461 enhanced radiosensitivity, which is consistent with the findings of a previous study demonstrating that the lower levels of Bcl‐2 and higher levels of Bax were indicative of enhanced radiosensitivity.32 In addition, inhibition of MMP‐2 was also found to enhance radiosensitivity in lung cancer cells.33 Here, BAX is linked to lung cancer.