METTL3 and cancer: METTL3 is an RNA methyltransferase that can modify the biological occurrence, decay and translation control of mRNA by m6A.12 Recent studies demonstrated that METTL3‐mediated m6A modification was involved in regulating numerous genes in various types of cancer.12, 13, 14 However, the expression pattern and function of METTL3 in HB are not clear.