METTL3 was shown to participate in hepatocellular carcinoma (HCC) progression via mRNA m6A modification.13 RBM15 and METTL14 were reported to play oncogenic roles in leukemogenesis.29 In addition, YTHDF1 was elucidated to be an oncogene in colorectal cancer.30 However, less is known about the critical role of m6A‐related molecules in HB. Here, YTHDF1 is linked to hepatocellular carcinoma.