Further network analysis revealed that proteins overexpressed in type B thymomas, such as PTPRC, LCK, PTPN7, GRAP2, PLCG1, VAV1, and TYMS, were highly relevant to T‐cell receptor signaling, T helper cell signaling, cytotoxic T lymphocyte, and phagocytosis signaling pathways and played pivotal roles in proliferation and differentiation of lymphocytes. This evidence concerns the gene PTPRC and thymoma type B.