Further comparison of type B3 and TSCC proteome revealed a number of differential proteins with similar expression patterns: CNOT2/9 and SHMT1 were found with high abundance in type B3 thymoma, while the abundance of HTRA1, TIMP1, and VCAN was higher in TSCC than in type B3 thymoma (Figs 6D and Fig. S8B). Here, VCAN is linked to thymoma.