The predominance of IgA class of aβ2GPI in our RA patients is in agreement with our previous studies on the frequency of aβ2GPI in other autoimmune diseases (Table 5).13, 16, 17, 18 Indeed, it has been reported that IgA is the predominant isotype of aPL antibodies in Afro‐Caribbeans19 and also in Afro‐Americans.20 The gene discussed is FASLG; the disease is autoimmune disease.