FASLG and vascular disorder: The resulting aβ2GPI is responsible for cartilage degradation of phospholipid bilayers and, therefore, boundary‐lubricating ability is deactivated.28 Moreover, through multiple mechanisms, aPL activity results not only in vasculopathy, thrombosis, and pregnancy complications but also in inflammation.3 So, could aβ2GPI be both the cause and the consequence of the inflammation in the synovial joints?