Univariate logistic regression analysis exhibited that miR‐125a (OR = 1.952, P = .006), miR‐125b (OR = 1.621, P < .001), age (OR = 1.052, P = .008), smoke (OR = 2.348, P = .022), COPD (OR = 3.687, P = .005), CRP (OR = 1.012, P < .001), APACHE II score (OR = 1.113, P = .001), and SOFA score (OR = 1.126, P = .040) was positively associated with ARDS risk in sepsis patients (Table 2). The gene discussed is CRP; the disease is chronic obstructive pulmonary disease.